Approved Use

Repatha® is an injectable prescription medicine used:

  • in adults with cardiovascular disease to reduce the risk of heart Read more attack, stroke, and certain types of heart surgery Read more
  • along with diet alone or together with other cholesterol-lowering medicines in adults with high blood cholesterol levels called primary hyperlipidemia (including a type of high cholesterol called heterozygous familial hypercholesterolemia) to reduce low-density lipoprotein (LDL) or bad cholesterol

As you may already know, LDL cholesterol is often called bad cholesterol because it can build up in the walls of your arteries and form plaque, putting you at risk of a serious cardiovascular event, like a heart attack, stroke, stent, or bypass surgery.

High LDL puts you at risk

Because high LDL has no symptoms, you can't feel what’s happening inside of your body and may not know if you’re at risk for a cardiovascular event—but you are.

Uncontrolled high LDL leads to plaque buildup, which narrows and reduces blood flow through your arteries (the blood vessels that carry blood from your heart to other parts of the body). This restriction of blood flow puts you at risk of a heart attack, stroke, stent, bypass surgery, or other heart problems.

DID YOU KNOW? After having a heart attack or stroke, the risk of another cardiovascular event is 1 in 3

You need to lower your LDL bad cholesterol

One of the most important things you can change to lower your risk of a cardiovascular event, like a heart attack or stroke, is your LDL.

Different factors can affect your cholesterol levels, like diet, weight, lack of exercise, and gender. High cholesterol can also run in families. Diet improvements and increased exercise can help to lower LDL, but sometimes you need to do more.

That’s why it’s important to take this seriously and talk to your doctor about lifestyle changes and cholesterol-lowering medicines to find a path toward lower LDL and a reduced risk of a devastating heart attack or stroke.

Talk to your doctor about high LDL

Get talking points about a different way to reduce your risk of a heart attack or stroke.

Start the conversation

Need extra resources to help lower your LDL?

Get additional information to help manage your LDL treatment with these helpful online cholesterol resources.

Learn more

Important Safety Information

Do not use Repatha® if you are allergic to evolocumab or to any of the ingredients in Repatha®.

Before you start using Repatha®, tell your healthcare provider about all your medical conditions, including if you are allergic to rubber or latex, are pregnant or plan to become pregnant, or are breastfeeding or plan to breastfeed. The needle covers on the single-use prefilled syringes and the inside of the needle caps on the single-use prefilled SureClick® autoinjectors contain dry natural rubber. The single-use Pushtronex® system (on-body infusor with prefilled cartridge) is not made with natural rubber latex.

Tell your healthcare provider or pharmacist about any prescription and over-the-counter medicines, vitamins, or herbal supplements you take.

What are the possible side effects of Repatha®?

Repatha® can cause serious side effects including: Repatha® may cause allergic reactions that can be serious. Call your healthcare provider or go to the nearest hospital emergency room right away if you have any symptoms of an allergic reaction including a severe rash, redness, severe itching, a swollen face, or trouble breathing.

The most common side effects of Repatha® include: runny nose, sore throat, symptoms of the common cold, flu or flu-like symptoms, back pain, high blood sugar levels (diabetes), and redness, pain, or bruising at the injection site.

Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of Repatha®. Ask your healthcare provider or pharmacist for more information. Call your healthcare provider for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Important Safety Information

Do not use Repatha® if you are allergic to evolocumab or to any of the ingredients in Repatha®.

Before you start using Repatha®, tell your healthcare provider about all your medical conditions, including if you are allergic to rubber or latex, are pregnant or plan to become pregnant, or are breastfeeding or plan to breastfeed. The needle covers on the single-use prefilled syringes and the inside of the needle caps on the single-use prefilled SureClick® autoinjectors contain dry natural rubber. The single-use Pushtronex® system (on-body infusor with prefilled cartridge) is not made with natural rubber latex.

Tell your healthcare provider or pharmacist about any prescription and over-the-counter medicines, vitamins, or herbal supplements you take.

What are the possible side effects of Repatha®?

Repatha® can cause serious side effects including: Repatha® may cause allergic reactions that can be serious. Call your healthcare provider or go to the nearest hospital emergency room right away if you have any symptoms of an allergic reaction including a severe rash, redness, severe itching, a swollen face, or trouble breathing.

The most common side effects of Repatha® include: runny nose, sore throat, symptoms of the common cold, flu or flu-like symptoms, back pain, high blood sugar levels (diabetes), and redness, pain, or bruising at the injection site.

Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of Repatha®. Ask your healthcare provider or pharmacist for more information. Call your healthcare provider for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.